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Cancer Research

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Frontiers in Cancer Research

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This is the ideal book for anyone contemplating starting a career in, or shifting their career to, studying the dynamics that drive cancer progression and ...

  • L'auteur :
  • Editeur: Springer
  • ISBN: 1493964607
  • Genre: Medical
  • Nombre de pages: 258
  • Langue: French/English
  • Vues: 628
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Détails: This is the ideal book for anyone contemplating starting a career in, or shifting their career to, studying the dynamics that drive cancer progression and its response to therapy. Topics include the theory and population genetics of cancers, genetic diversity within tumors (intra-tumor heterogeneity), understanding how mutant clones expand in tissues, the role of cancer stem cells in the dynamics of tumors, the evolution of metastasis, and how to improve cancer therapy by addressing the evolution of cancers in response to our interventions. There are also chapters on the patterns of cancer susceptibility in humans due to a mismatch between our modern environment and the environment in which our ancestors evolved, as well as a chapter on the evolution of cancer suppression mechanisms that have evolved in different species, particularly the large long-lived animals like elephants and whales that are better at suppressing cancers than humans. This book serves as a primer on the evolutionary and ecological theory of cancer- the framework upon which all the details of cancer may be hung. It is ideal for oncologists and cancer researchers interested in evolutionary theory, and evolutionary biologists and ecologists interested in gaining insights into cancer development and prevention.


The Genetics of Cancer

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It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics a ...

  • L'auteur : B.A. Ponder,M.J. Waring
  • Editeur: Springer Science & Business Media
  • ISBN: 9401106770
  • Genre: Medical
  • Nombre de pages: 221
  • Langue: French/English
  • Vues: 1232
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Détails: It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics and epidemiology have combined to define the role of inheritance in cancer more clearly, and to identify some of the genes involved. The causative genes can be tracked through cancer-prone families via genetic linkage and positional cloning. Several of the genes discovered have subsequently been proved to play critical roles in normal growth and development. There are also implications for the families themselves in terms of genetic testing with its attendant dilemmas, if it is not clear that useful action will result. The chapters in The Genetics of Cancer illustrate what has already been achieved and take a critical look at the future directions of this research and its potential clinical applications.


The Immortal Life of Henrietta Lacks

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#1 NEW YORK TIMES BESTSELLER • “The story of modern medicine and bioethics—and, indeed, race relations—is refracted beautifully, and movingly.” ...

  • L'auteur : Rebecca Skloot
  • Editeur: Crown
  • ISBN: 0307589382
  • Genre: Science
  • Nombre de pages: 400
  • Langue: French/English
  • Vues: 337
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Détails: #1 NEW YORK TIMES BESTSELLER • “The story of modern medicine and bioethics—and, indeed, race relations—is refracted beautifully, and movingly.”—Entertainment Weekly NOW A MAJOR MOTION PICTURE FROM HBO® STARRING OPRAH WINFREY AND ROSE BYRNE • ONE OF THE “MOST INFLUENTIAL” (CNN), “DEFINING” (LITHUB), AND “BEST” (THE PHILADELPHIA INQUIRER) BOOKS OF THE DECADE • ONE OF ESSENCE’S 50 MOST IMPACTFUL BLACK BOOKS OF THE PAST 50 YEARS • WINNER OF THE CHICAGO TRIBUNE HEARTLAND PRIZE FOR NONFICTION NAMED ONE OF THE BEST BOOKS OF THE YEAR BY The New York Times Book Review • Entertainment Weekly • O: The Oprah Magazine • NPR • Financial Times • New York • Independent (U.K.) • Times (U.K.) • Publishers Weekly • Library Journal • Kirkus Reviews • Booklist • Globe and Mail Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine: The first “immortal” human cells grown in culture, which are still alive today, though she has been dead for more than sixty years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions. Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave. Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family—past and present—is inextricably connected to the dark history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of. Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah. Deborah was consumed with questions: Had scientists cloned her mother? Had they killed her to harvest her cells? And if her mother was so important to medicine, why couldn’t her children afford health insurance? Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.


Advances in Cancer Research

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The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. This volume stands as the ...

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  • Editeur: Elsevier
  • ISBN: 9780080471013
  • Genre: Science
  • Nombre de pages: 432
  • Langue: French/English
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Détails: The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. This volume stands as the first ever thematic volume in the series, focusing on the topic of genomics in cancer drug development. The chapters included in this book represent the cutting-edge information in the field and span such topics as Mass Spectrometry: Uncovering the Cancer Proteome for Diagnostics; Biomarker Discovery in Epithelial Ovarian Cancer by Genomic Approaches; The Application of siRNA Technology to Cancer Biology Discovery; Ribozyme Technology for Cancer Gene Target Identification and Validation; Cancer Cell-Based Genomic and Small Molecule Screens; Tumour Antigens as Surrogate Markers and Targets for Therapy and Vaccines; Practices and Pitfalls of Mouse Cancer Models in Drug Discovery; Biomarker Assay Translation from Discovery to Clinical Studies in Cancer Drug Development – Quantification of Emerging Protein Biomarkers; Molecular Optical Imaging of Therapeutic Targets of Cancer; Cancer Drug Approval in the United States, Europe and Japan.


Treatment of Cancer

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Treatment of Cancer is a multi-author work and comprehensive guide on modern cancer treatment that aims to give clinician and student alike the framework f ...

  • L'auteur : Pat Price,Karol Sikora
  • Editeur: CRC Press
  • ISBN: 0429649002
  • Genre: Medical
  • Nombre de pages: 614
  • Langue: French/English
  • Vues: 1640
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Détails: Treatment of Cancer is a multi-author work and comprehensive guide on modern cancer treatment that aims to give clinician and student alike the framework for an integrated approach to patient care, including radiotherapy, chemotherapy, and surgery. Much information is presented in tables and charts for easy assimilation, and clear algorithms for patient pathways are included to make decisions straightforward while allowing for sound clinical judgement.


Recent Advances in Cancer Research and Therapy

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Cancer continues to be one of the major causes of death throughout the developed world, which has led to increased research on effective treatments. Becaus ...

  • L'auteur : Xin-Yuan Liu,Sidney Pestka,Yu-Fang Shi
  • Editeur: Elsevier
  • ISBN: 012397836X
  • Genre: Medical
  • Nombre de pages: 700
  • Langue: French/English
  • Vues: 449
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Détails: Cancer continues to be one of the major causes of death throughout the developed world, which has led to increased research on effective treatments. Because of this, in the past decade, rapid progress in the field of cancer treatment has been seen. Recent Advances in Cancer Research and Therapy reviews in specific details some of the most effective and promising treatments developed in research centers worldwide. While referencing advances in traditional therapies and treatments such as chemotherapy, this book also highlights advances in biotherapy including research using Interferon and Super Interferon, HecI based and liposome based therapy, gene therapy, and p53 based cancer therapy. There is also a discussion of current cancer research in China including traditional Chinese medicine. Written by leading scientists in the field, this book provides an essential insight into the current state of cancer therapy and treatment. Includes a wide range of research areas including a focus on biotherapy and the development of novel cancer therapeutic strategies. Formatted for a broad audience including all working in researching cancer treatments and therapies. Discusses special traits and results of Chinese cancer research.


Making Health Communication Programs Work

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Discusses key principles relative to specific steps in health communications program development, and includes examples of their use. Covers: planning and ...

  • L'auteur :
  • Editeur: DIANE Publishing
  • ISBN: 0788100807
  • Genre: Health & Fitness
  • Nombre de pages: 131
  • Langue: French/English
  • Vues: 1794
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Détails: Discusses key principles relative to specific steps in health communications program development, and includes examples of their use. Covers: planning and strategy selection, selecting channels and materials, developing materials and pretesting (pretesting -- what it can and cannot do, pretesting methods, plan and conduct pretests), implementing your program, assessing effectiveness, feedback to refine program and more. Each chapter includes a 3selected readings2 section. Includes: information sources, sample forms, glossary, bibliography, etc. Photos and drawings.


Immunotherapy in Translational Cancer Research

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A guide to state-of-the-art cancer immunotherapy in translational cancer research A volume in the Translational Oncology series, Immunotherapy in Translati ...

  • L'auteur : Laurence J. N. Cooper,Elizabeth A. Mittendorf,Judy Moyes,Sabitha Prabhakaran
  • Editeur: John Wiley & Sons
  • ISBN: 1118684508
  • Genre: Medical
  • Nombre de pages: 312
  • Langue: French/English
  • Vues: 970
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Détails: A guide to state-of-the-art cancer immunotherapy in translational cancer research A volume in the Translational Oncology series, Immunotherapy in Translational Cancer Research explores the recent developments in the role that immunotherapy plays in the treatment of a wide range of cancers. The editors present key concepts, illustrative examples, and suggest alternative strategies in order to achieve individualized targeted therapy. Comprehensive in scope, Immunotherapy in Translational Cancer Research reviews the relevant history, current state, and the future of burgeoning cancer-fighting therapies. The book also includes critical information on drug development, clinical trials, and governmental resources and regulatory issues. Each chapter is created to feature: development of the immunotherapy; challenges that have been overcome in order to scale up and undertake clinical trials; and clinical experience and application of research. This authoritative volume is edited by a team of noted experts from MD Anderson Cancer Center, the world’s foremost cancer research and care center and: Offers a comprehensive presentation of state-of-the-art cancer immunotherapy research that accelerates the pace of clinical cancer care Filled with the concepts, examples, and approaches for developing individualized therapy Explores the breath of treatments that reflect the complexity of the immune system itself Includes contributions from a panel international experts in the field of immunotherapy Designed for physicians, medical students, scientists, pharmaceutical executives, public health and public policy government leaders and community oncologists, this essential resource offers a guide to the bidirectional interaction between laboratory and clinic immunotherapy cancer research.


Spheroids in Cancer Research

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Malignant growth of cells is often characterized by disorganization of tissue structure, abnormal blood vessel development, and insuffi cient vascular supp ...

  • L'auteur : H. Acker,J. Carlsson,R. Durand,R.M. Sutherland
  • Editeur: Springer Science & Business Media
  • ISBN: 3642823408
  • Genre: Medical
  • Nombre de pages: 186
  • Langue: French/English
  • Vues: 1697
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Détails: Malignant growth of cells is often characterized by disorganization of tissue structure, abnormal blood vessel development, and insuffi cient vascular supply. As a consequence, the cancer cells grow in a three-dimensional pattern in atypical microenvironments which include physical, chemical, and nutritional stresses. Necrosis often develops some distance away from the blood vessels. In association with an inherent instability in malignant cell populations, and also because of the changing micromilieu, significant cellular heteroge neity emerges with regard to various phenotypic characteristics. Both biological behavior and responses to therapeutic agents can be affected. A variety of in vitro and in vivo experimental models exist for research on properties of cancer cells during growth. The multicell spheroid model was developed as a system of intermediate complexity in which three dimensional growth of cells enhances cell-cell interactions and creates micro environments that simulate the conditions in intervascular microregions of tumors or microme tastatic foci. Spheroids may change their cellular characteristics with changing environments during growth. These can be studied under controlled conditions in vitro. Interest in details of experimental methods for this model system stimulated the organization of the First International Conference in Rochester, NY in 1980, the Proceedings of which were summarized in Cancer Research in 1981. Since then there has been a rapid increase in the use of this model system, and increased research on the significance of cell-cell and cell-microenvironment interactions in biology in general.


Transforming Clinical Research in the United States

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An ideal health care system relies on efficiently generating timely, accurate evidence to deliver on its promise of diminishing the divide between clinical ...

  • L'auteur : Institute of Medicine,Board on Health Sciences Policy,Forum on Drug Discovery, Development, and Translation
  • Editeur: National Academies Press
  • ISBN: 9780309163354
  • Genre: Medical
  • Nombre de pages: 150
  • Langue: French/English
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Détails: An ideal health care system relies on efficiently generating timely, accurate evidence to deliver on its promise of diminishing the divide between clinical practice and research. There are growing indications, however, that the current health care system and the clinical research that guides medical decisions in the United States falls far short of this vision. The process of generating medical evidence through clinical trials in the United States is expensive and lengthy, includes a number of regulatory hurdles, and is based on a limited infrastructure. The link between clinical research and medical progress is also frequently misunderstood or unsupported by both patients and providers. The focus of clinical research changes as diseases emerge and new treatments create cures for old conditions. As diseases evolve, the ultimate goal remains to speed new and improved medical treatments to patients throughout the world. To keep pace with rapidly changing health care demands, clinical research resources need to be organized and on hand to address the numerous health care questions that continually emerge. Improving the overall capacity of the clinical research enterprise will depend on ensuring that there is an adequate infrastructure in place to support the investigators who conduct research, the patients with real diseases who volunteer to participate in experimental research, and the institutions that organize and carry out the trials. To address these issues and better understand the current state of clinical research in the United States, the Institute of Medicine's (IOM) Forum on Drug Discovery, Development, and Translation held a 2-day workshop entitled Transforming Clinical Research in the United States. The workshop, summarized in this volume, laid the foundation for a broader initiative of the Forum addressing different aspects of clinical research. Future Forum plans include further examining regulatory, administrative, and structural barriers to the effective conduct of clinical research; developing a vision for a stable, continuously funded clinical research infrastructure in the United States; and considering strategies and collaborative activities to facilitate more robust public engagement in the clinical research enterprise.


NMR Metabolomics in Cancer Research

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The application of nuclear magnetic resonance (NMR) metabolomics in cancer research requires an understanding of the many possibilities that NMR metabolomi ...

  • L'auteur : Miroslava Čuperlović-Culf
  • Editeur: Elsevier
  • ISBN: 1908818263
  • Genre: Medical
  • Nombre de pages: 446
  • Langue: French/English
  • Vues: 365
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Détails: The application of nuclear magnetic resonance (NMR) metabolomics in cancer research requires an understanding of the many possibilities that NMR metabolomics can offer, as well as of the specific characteristics of the cancer metabolic phenotype and the open questions in cancer research. NMR metabolomics in cancer research presents a detailed account of the NMR spectroscopy methods applied to metabolomics mixture analysis along with a discussion of their advantages and disadvantages. Following an overview of the potential use of NMR metabolomics in cancer research, the book begins with an examination of the cancer metabolic phenotype and experimental methodology, before moving on to cover data pre-processing and data analysis. Chapters in the latter part of the book look at dynamic metabolic profiling, biomarker discovery, and the application of NMR metabolomics for different types of cancer, before a concluding chapter discusses future perspectives in the field. Focused description of NMR spectroscopy needed by cancer biologists who are starting to use metabolomics Current overview of knowledge related to the cancer metabolic phenotype from the perspective of metabolomics applications Information about the best practices in NMR metabolomics experimentation and data preprocessing as applied to different sample types


Life Over Cancer

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Dr. Keith Block is at the global vanguard of innovative cancer care. As medical director of the Block Center for Integrative Cancer Treatment in Evanston, ...

  • L'auteur : Keith Block
  • Editeur: Bantam
  • ISBN: 0553906380
  • Genre: Health & Fitness
  • Nombre de pages: 608
  • Langue: French/English
  • Vues: 770
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Détails: Dr. Keith Block is at the global vanguard of innovative cancer care. As medical director of the Block Center for Integrative Cancer Treatment in Evanston, Illinois, he has treated thousands of patients who have lived long, full lives beyond their original prognoses. Now he has distilled almost thirty years of experience into the first book that gives patients a systematic, research-based plan for developing the physical and emotional vitality they need to meet the demands of treatment and recovery. Based on a profound understanding of how body and mind can work together to defeat disease, this groundbreaking book offers: • Innovative approaches to conventional treatments, such as “chronotherapy”–chemotherapy timed to patients’ unique circadian rhythms for enhanced effectiveness and reduced toxicity • Dietary choices that make the biochemical environment hostile to cancer growth and recurrence, and strengthen the immune system’s ability to attack remaining cancer cells • Precise supplement protocols to tame treatment side effects, relieve disease-related symptoms, and modify processes like inflammation and glycemia that can fuel cancer if left untreated • A new paradigm for exercise and stress reduction that restores your strength, reduces anxiety and depression, and supports the body’s own ability to heal • A complete program for remission maintenance–a proactive plan to make sure the cancer never returns Also included are “quick-start” maps to help you find the information you need right now and many case histories that will support and inspire you. Encouraging, compassionate, and authoritative, Life over Cancer is the guide patients everywhere have been waiting for.


Next Generation Sequencing in Cancer Research

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​​​​This volume provides an interdisciplinary perspective of applying Next Generation Sequencing (NGS) technology to cancer research. It aims to sy ...

  • L'auteur : Wei Wu,Hani Choudhry
  • Editeur: Springer Science & Business Media
  • ISBN: 1461476453
  • Genre: Medical
  • Nombre de pages: 383
  • Langue: French/English
  • Vues: 1176
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Détails: ​​​​This volume provides an interdisciplinary perspective of applying Next Generation Sequencing (NGS) technology to cancer research. It aims to systematically introduce the concept of NGS, a variety of NGS platforms and their practical implications in cancer biology.This unique and comprehensive text will integrate the unprecedented NGS technology into various cancer research projects as opposed to most books which offer a detailed description of the technology. This volume will present true experimental results with concrete data processing pipelines, discuss the bottleneck of each platform for real project in cancer research. In additional, single cancer cell sequencing as the proof of concept will be introduced in this book, along with cutting-edge information provided will help the intended audience to develop a comprehensive understanding of the NGS technology and practical whole genome sequencing data analysis and rapidly translate into their own research, specifically in the field of cancer biology.


Taking Charge of Cancer

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A critical resource for anyone with a cancer diagnosis. Written by a radiation oncologist and cancer researcher, Taking Charge of Cancer offers an insider ...

  • L'auteur : David Palma
  • Editeur: New Harbinger Publications
  • ISBN: 1626258643
  • Genre: Health & Fitness
  • Nombre de pages: 240
  • Langue: French/English
  • Vues: 1201
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Détails: A critical resource for anyone with a cancer diagnosis. Written by a radiation oncologist and cancer researcher, Taking Charge of Cancer offers an insider’s guide to understanding and receiving the best treatment options, choosing the right medical team, and approaching this difficult time with knowledge and hope. Receiving a cancer diagnosis can be terrifying, and the first thing you probably want to know is: How am I going to survive this? Cancer care requires decisions from numerous professionals, delivering treatments that are potentially life-saving, but also potentially dangerous and life-threatening. The chances of cure and survival for any given patient depend on the expertise of the cancer team, and whether procedures are in place to ensure that cancer care is delivered properly. So, how can you make sure you choose the right treatment team and ensure the best chances of survival and long-term health after being diagnosed with cancer? Taking Charge of Cancer is a different type of book for cancer patients—one that goes beyond the cancer information that is currently available, allowing you to truly take control of your cancer treatment. You’ll learn how to obtain and understand medical records, and why these records are critical to your care. You’ll also find the tools you’ll need to determine if the recommendations made by doctors are in keeping with accepted treatment guidelines. You’ll discover how doctors use evidence to decide which treatments are best, as well as how doctors can become biased in their recommendations. And, most importantly, you’ll be able to evaluate whether surgery, radiation, or chemotherapy make the most sense in your specific case—and whether or not these serious treatments are being delivered effectively and safely according to the highest standards. Now that you’ve received a cancer diagnosis, it’s time to set a plan in motion for your recovery. This book will help you do just that—every step of the way.


Laser Cancer Research

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together with the oncologist. For man, the laser must be moved out of the laboratory into the operating room. At present, its true position in the cancer t ...

  • L'auteur : Leon Goldman
  • Editeur: Springer Science & Business Media
  • ISBN: 3642872689
  • Genre: Medical
  • Nombre de pages: 66
  • Langue: French/English
  • Vues: 1168
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Détails: together with the oncologist. For man, the laser must be moved out of the laboratory into the operating room. At present, its true position in the cancer therapy program is not yet known. The greatest attention is being directed to melanoma because of the tremendous energy adsorption capabilities of this heavily pigmented tumor. The next area of interest is in uncommon and com mon tumors of blood vessels. Here, too, the color factor influences to a signifi cant degree the absorption of the laser. Multiple accessible malignancies are treated also by the laser chiefly to compare the effect here with other modalities of therapy. Finally, as a type of therapy of desperation, lasers are used in the treatment of metastatic lesions. This then, is the brief introduction to the study of the current status of laser cancer research. Intense, difficult and cooperative research of the next few years will determine the role of the laser, an "optical knife", as an investi gative or therapeutic instrument. T able of Contents Chapter 1 Laser Instrumentation 1 Chapter 2 Laser Protection . 8 Chapter 3 The Laser Reaction in Tissue 13 Chapter 4 Color Qualities of Tissue in Relation to Laser Radiation 16 Chapter 5 Laser Radiation of Tissue Cultures .


High-Dimensional Data Analysis in Cancer Research

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Multivariate analysis is a mainstay of statistical tools in the analysis of biomedical data. It concerns with associating data matrices of n rows by p colu ...

  • L'auteur : Xiaochun Li,Ronghui Xu
  • Editeur: Springer Science & Business Media
  • ISBN: 0387697659
  • Genre: Medical
  • Nombre de pages: 392
  • Langue: French/English
  • Vues: 890
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Détails: Multivariate analysis is a mainstay of statistical tools in the analysis of biomedical data. It concerns with associating data matrices of n rows by p columns, with rows representing samples (or patients) and columns attributes of samples, to some response variables, e.g., patients outcome. Classically, the sample size n is much larger than p, the number of variables. The properties of statistical models have been mostly discussed under the assumption of fixed p and infinite n. The advance of biological sciences and technologies has revolutionized the process of investigations of cancer. The biomedical data collection has become more automatic and more extensive. We are in the era of p as a large fraction of n, and even much larger than n. Take proteomics as an example. Although proteomic techniques have been researched and developed for many decades to identify proteins or peptides uniquely associated with a given disease state, until recently this has been mostly a laborious process, carried out one protein at a time. The advent of high throughput proteome-wide technologies such as liquid chromatography-tandem mass spectroscopy make it possible to generate proteomic signatures that facilitate rapid development of new strategies for proteomics-based detection of disease. This poses new challenges and calls for scalable solutions to the analysis of such high dimensional data. In this volume, we will present the systematic and analytical approaches and strategies from both biostatistics and bioinformatics to the analysis of correlated and high-dimensional data.


Molecular Pathology in Cancer Research

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The aim of the book is to discuss the application of molecular pathology in cancer research, and its contribution in the classification of different tumors ...

  • L'auteur : Sunil R. Lakhani,Stephen B. Fox
  • Editeur: Springer
  • ISBN: 149396643X
  • Genre: Medical
  • Nombre de pages: 369
  • Langue: French/English
  • Vues: 1646
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Détails: The aim of the book is to discuss the application of molecular pathology in cancer research, and its contribution in the classification of different tumors and identification of potential molecular targets, as well as how this knowledge may be translated into clinical practice, and the huge impact this field is likely to have in the next 5 to 10 years.


Spheroid Culture in Cancer Research (1991)

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Spheroid Culture in Cancer Research describes the various techniques now available for establishing spheroid tissue culture, including spheroid culture fro ...

  • L'auteur : Rolf Bjerkvig
  • Editeur: CRC Press
  • ISBN: 135135762X
  • Genre: Medical
  • Nombre de pages: 344
  • Langue: French/English
  • Vues: 708
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Détails: Spheroid Culture in Cancer Research describes the various techniques now available for establishing spheroid tissue culture, including spheroid culture from normal tissues and from tumor cell lines. The book also describes how the spheroid system can be used to study interactions between normal and malignant cells. Microenvironmental conditions in spheroids and how this micromilieu may promote cellular heterogeneity and histiotypic structures not observed in corresponding monolayer cultures are discussed. The biological importance of oxygen tension, pH gradients, diffusions of nutrients, and cell-cell communication in spheroids are also examined. The book will be profoundly important to researchers in experimental chemotherapy, radiotherapy, immunotherapy, and hyperthermia.


DNA Microarray Technology and Data Analysis in Cancer Research

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...

  • L'auteur :
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  • ISBN: 981447200X
  • Genre:
  • Nombre de pages: N.A
  • Langue: French/English
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Hyperthermia In Cancer Treatment: A Primer

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Following an introductory overview, Hyperthermia In Cancer Treatment: A Primer comprehensively describes the biological reasons for associating hyperthermi ...

  • L'auteur : Gian F. Baronzio,E. Dieter Hager
  • Editeur: Springer Science & Business Media
  • ISBN: 9780387334417
  • Genre: Medical
  • Nombre de pages: 366
  • Langue: French/English
  • Vues: 734
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Détails: Following an introductory overview, Hyperthermia In Cancer Treatment: A Primer comprehensively describes the biological reasons for associating hyperthermia with radiation and chemotherapy and the biological and clinical effects of hyperthermia on cancerous and normal tissues. The volume’s 20 chapters are arranged in three principal parts: physical and methodological studies, biologic principles, and clinical studies.


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