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Epigenetic Principles of Evolution

Telecharger pdf Epigenetic Principles of Evolution

This is the first and only book, so far, to deal with the causal basis of evolution from an epigenetic view. By revealing the epigenetic \"user\" of the \" ...

  • L'auteur : ,
  • Editeur: Elsevier
  • ISBN: 012415851X
  • Genre: Science
  • Nombre de pages: 846
  • Langue: French/English
  • Vues: 1086
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Détails: This is the first and only book, so far, to deal with the causal basis of evolution from an epigenetic view. By revealing the epigenetic "user" of the "genetic toolkit", this book demonstrates the primacy of epigenetic mechanisms and epigenetic information in generating evolutionary novelties. The author convincingly supports his theory with a host of examples from the most varied fields of biology, by emphasizing changes in developmental pathways as the basic source of evolutionary change in metazoans. Original and thought provoking--a radically new theory that overcomes the present difficulties of the theory of evolution Is the first and only theory that uses epigenetic mechanisms and principles for explaining evolution of metazoans Takes an integrative approach and shows a wide range of learning


Biomaterials

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Biomaterials are produced from biological material and are used for their physical characteristics. This book looks at the range of biomaterials and their ...

  • L'auteur : David Byrom
  • Editeur: Springer
  • ISBN: 1349111678
  • Genre: Science
  • Nombre de pages: 365
  • Langue: French/English
  • Vues: 862
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Détails: Biomaterials are produced from biological material and are used for their physical characteristics. This book looks at the range of biomaterials and their applications which range from the use of polysaccharides as thickening agents to the use of proteins as fibres and adhesives.


Repetitive DNA

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The experimental data that have been generated using new molecular techniques associated with the completion of genome projects have changed our perception ...

  • L'auteur : M.A. Garrido-Ramos
  • Editeur: Karger Medical and Scientific Publishers
  • ISBN: 3318021504
  • Genre: Medical
  • Nombre de pages: 238
  • Langue: French/English
  • Vues: 1646
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Détails: The experimental data that have been generated using new molecular techniques associated with the completion of genome projects have changed our perception of the structural features, functional implications and evolutionary dynamics of repetitive DNA sequences. This volume of Genome Dynamics provides a valuable update on recent developments in research into multigene families, centromeres, telomeres, microsatellite DNA, satellite DNA, and transposable elements. Each chapter presents a review by distinguished experts and analyzes repetitive DNA diversity and abundance, as well as the impact on genome structure, function and evolution.This publication is targeted at scientists and scholars at every level, from students to faculty members, and, indeed, anyone involved or interested in genetics, molecular evolution, molecular biology as well as genomics will find it a valuable source of up-to-date information.


Gene Silencing by RNA Interference

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Maximizing the potential of RNA interference in functional genomics - as well as in the development of therapeutics - continues to be at the forefront of b ...

  • L'auteur : Muhammad Sohail
  • Editeur: CRC Press
  • ISBN: 020348925X
  • Genre: Science
  • Nombre de pages: 400
  • Langue: French/English
  • Vues: 769
  • Telecharger: 769
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Détails: Maximizing the potential of RNA interference in functional genomics - as well as in the development of therapeutics - continues to be at the forefront of biomedical research. Unlike journal articles, Gene Silencing by RNA Interference: Technology and Application combines essential background to the RNAi field with practical techniques designed by renowned researchers to provide the most diverse and in-depth examination of the subject yet. This book describes methods and protocols for gene silencing and RNA interference. Each chapter provides necessary background to the subject and then gives detailed methods in easy-to-follow steps, along with troubleshooting hints and tips. Following a general and historical introduction, chapters two through eight focus on technical details of the various methods of siRNA design, chemical and enzymatic production, plasmid- and virus-mediated intracellular expression, and other RNAi tools. Chapter nine discusses the exogenous delivery of siRNAs into cells, and the final chapters of the book detail the application of RNAi to dissect gene function in a number of biological systems, including cell-free systems, cultured cells, and whole organisms. From the design and production of RNAi tools to their applications, Gene Silencing by RNA Interference: Technology and Application is the first to present the entire spectrum of activity, design, production, and delivery of RNAi reagents, providing a welcome guide for both academic and commercial use.


Manual for Soil Analysis - Monitoring and Assessing Soil Bioremediation

Telecharger pdf Manual for Soil Analysis - Monitoring and Assessing Soil Bioremediation

This volume presents detailed descriptions of methods for evaluating, monitoring and assessing bioremediation of soil contaminated with organic pollutants ...

  • L'auteur : Rosa Margesin,Franz Schinner
  • Editeur: Springer Science & Business Media
  • ISBN: 3540289046
  • Genre: Nature
  • Nombre de pages: 366
  • Langue: French/English
  • Vues: 495
  • Telecharger: 495
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Détails: This volume presents detailed descriptions of methods for evaluating, monitoring and assessing bioremediation of soil contaminated with organic pollutants or heavy metals. Traditional soil investigation techniques, including chemical, physical and microbiological methods, are complemented by the most suitable modern methods, including bioreporter technology, immunological, ecotoxicological and molecular assays. Step-by-step procedures, lists of required equipment and reagents and notes on evaluation and quality control allow immediate application


Converging Technologies for Improving Human Performance

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M. C. Roco and W.S. Bainbridge In the early decades of the 21st century, concentrated efforts can unify science based on the unity of nature, thereby advan ...

  • L'auteur : William Sims Bainbridge
  • Editeur: Springer Science & Business Media
  • ISBN: 9401703590
  • Genre: Technology & Engineering
  • Nombre de pages: 468
  • Langue: French/English
  • Vues: 655
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Détails: M. C. Roco and W.S. Bainbridge In the early decades of the 21st century, concentrated efforts can unify science based on the unity of nature, thereby advancing the combination of nanotechnology, biotechnology, information technology, and new technologies based in cognitive science. With proper attention to ethical issues and societal needs, converging in human abilities, societal technologies could achieve a tremendous improvement outcomes, the nation's productivity, and the quality of life. This is a broad, cross cutting, emerging and timely opportunity of interest to individuals, society and humanity in the long term. The phrase "convergent technologies" refers to the synergistic combination of four major "NBIC" (nano-bio-info-cogno) provinces of science and technology, each of which is currently progressing at a rapid rate: (a) nanoscience and nanotechnology; (b) biotechnology and biomedicine, including genetic engineering; (c) information technology, including advanced computing and communications; (d) cognitive science, including cognitive neuroscience. Timely and Broad Opportunity. Convergence of diverse technologies is based on material unity at the nanoscale and on technology integration from that scale.


Introduction to Protein Structure

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The VitalBook e-book of Introduction to Protein Structure, Second Edition is inly available in the US and Canada at the present time. To purchase or rent p ...

  • L'auteur : Carl Ivar Branden,John Tooze
  • Editeur: Garland Science
  • ISBN: 1136969896
  • Genre: Science
  • Nombre de pages: 424
  • Langue: French/English
  • Vues: 1549
  • Telecharger: 1549
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Détails: The VitalBook e-book of Introduction to Protein Structure, Second Edition is inly available in the US and Canada at the present time. To purchase or rent please visit http://store.vitalsource.com/show/9780815323051Introduction to Protein Structure provides an account of the principles of protein structure, with examples of key proteins in their bio


Evolutionary Quantitative Genetics

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The impetus for this book arose out of my previous book, The Evolution of Life Histories (Roff, 1992). In that book I presented a single chapter on quanti ...

  • L'auteur : Derek A. Roff
  • Editeur: Springer Science & Business Media
  • ISBN: 1461540801
  • Genre: Science
  • Nombre de pages: 494
  • Langue: French/English
  • Vues: 1821
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Détails: The impetus for this book arose out of my previous book, The Evolution of Life Histories (Roff, 1992). In that book I presented a single chapter on quanti tative genetic theory. However, as the book was concerned with the evolution of life histories and traits connected to this, the presence of quantitative genetic variation was an underlying theme throughout. Much of the focus was placed on optimality theory, for it is this approach that has proven to be extremely successful in the analysis of life history variation. But quantitative genetics cannot be ig nored, because there are some questions for which optimality approaches are inappropriate; for example, although optimality modeling can address the ques tion of the maintenance of phenotypic variation, it cannot say anything about genetic variation, on which further evolution clearly depends. The present book is, thus, a natural extension of the first. I have approached the problem not from the point of view of an animal or plant breeder but from that of one interested in understanding the evolution of quantitative traits in wild populations. The subject is large with a considerable body of theory: I generally present the assumptions underlying the analysis and the results, giving the relevant references for those interested in the intervening mathematics. My interest is in what quantitative genetics tells me about evolutionary processes; therefore, I have concentrated on areas of research most relevant to field studies.


Molecular Evolution and Phylogenetics

Telecharger pdf Molecular Evolution and Phylogenetics

During the last ten years, remarkable progress has occurred in the study of molecular evolution. Among the most important factors that are responsible for ...

  • L'auteur : Masatoshi Nei,Sudhir Kumar
  • Editeur: Oxford University Press
  • ISBN: 0199881227
  • Genre: Science
  • Nombre de pages: 352
  • Langue: French/English
  • Vues: 550
  • Telecharger: 550
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Détails: During the last ten years, remarkable progress has occurred in the study of molecular evolution. Among the most important factors that are responsible for this progress are the development of new statistical methods and advances in computational technology. In particular, phylogenetic analysis of DNA or protein sequences has become a powerful tool for studying molecular evolution. Along with this developing technology, the application of the new statistical and computational methods has become more complicated and there is no comprehensive volume that treats these methods in depth. Molecular Evolution and Phylogenetics fills this gap and present various statistical methods that are easily accessible to general biologists as well as biochemists, bioinformatists and graduate students. The text covers measurement of sequence divergence, construction of phylogenetic trees, statistical tests for detection of positive Darwinian selection, inference of ancestral amino acid sequences, construction of linearized trees, and analysis of allele frequency data. Emphasis is given to practical methods of data analysis, and methods can be learned by working through numerical examples using the computer program MEGA2 that is provided.


Virus Structure

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Virus Structure covers the full spectrum of modern structural virology. Its goal is to describe the means for defining moderate to high resolution structur ...

  • L'auteur : ,
  • Editeur: Elsevier
  • ISBN: 0080493777
  • Genre: Science
  • Nombre de pages: 543
  • Langue: French/English
  • Vues: 1523
  • Telecharger: 1523
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Détails: Virus Structure covers the full spectrum of modern structural virology. Its goal is to describe the means for defining moderate to high resolution structures and the basic principles that have emerged from these studies. Among the topics covered are Hybrid Vigor, Structural Folds of Viral Proteins, Virus Particle Dynamics, Viral Gemone Organization, Enveloped Viruses and Large Viruses. Covers viral assembly using heterologous expression systems and cell extracts Discusses molecular mechanisms in bacteriophage T7 procapsid assembly, maturation and DNA containment Includes information on structural studies on antibody/virus complexes


Big Data, Little Data, No Data

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An examination of the uses of data within a changing knowledge infrastructure, offering analysis and case studies from the sciences, social sciences, and h ...

  • L'auteur : Christine L. Borgman
  • Editeur: MIT Press
  • ISBN: 0262327872
  • Genre: Language Arts & Disciplines
  • Nombre de pages: 416
  • Langue: French/English
  • Vues: 1601
  • Telecharger: 1601
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Détails: An examination of the uses of data within a changing knowledge infrastructure, offering analysis and case studies from the sciences, social sciences, and humanities. “Big Data” is on the covers of Science, Nature, the Economist, and Wired magazines, on the front pages of the Wall Street Journal and the New York Times. But despite the media hyperbole, as Christine Borgman points out in this examination of data and scholarly research, having the right data is usually better than having more data; little data can be just as valuable as big data. In many cases, there are no data—because relevant data don't exist, cannot be found, or are not available. Moreover, data sharing is difficult, incentives to do so are minimal, and data practices vary widely across disciplines. Borgman, an often-cited authority on scholarly communication, argues that data have no value or meaning in isolation; they exist within a knowledge infrastructure—an ecology of people, practices, technologies, institutions, material objects, and relationships. After laying out the premises of her investigation—six “provocations” meant to inspire discussion about the uses of data in scholarship—Borgman offers case studies of data practices in the sciences, the social sciences, and the humanities, and then considers the implications of her findings for scholarly practice and research policy. To manage and exploit data over the long term, Borgman argues, requires massive investment in knowledge infrastructures; at stake is the future of scholarship.


Bacterial Genomes

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A wide range of microbiologists, molecular biologists, and molecular evolutionary biologists will find this new volume of singular interest. It summarizes ...

  • L'auteur : F.J. de Bruijn,James R. Lupski,G.M. Weinstock
  • Editeur: Springer Science & Business Media
  • ISBN: 1461563690
  • Genre: Science
  • Nombre de pages: 793
  • Langue: French/English
  • Vues: 1792
  • Telecharger: 1792
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Détails: A wide range of microbiologists, molecular biologists, and molecular evolutionary biologists will find this new volume of singular interest. It summarizes the present knowledge about the structure and stability of microbial genomes, and reviews the techniques used to analyze and fingerprint them. Maps of approximately thirty important microbes, along with articles on the construction and relevant features of the maps are included. The volume is not intended as a complete compendium of all information on microbial genomes, but rather focuses on approaches, methods and good examples of the analysis of small genomes.


Genetics of Sex Determination

Telecharger pdf Genetics of Sex Determination

The Genetical Theory of Natural Selection by R.A. Fisher (1930) dictated that sexual dimorphisms may depend upon a single medelian factor. This could be tr ...

  • L'auteur : R.S. Verma
  • Editeur: Elsevier
  • ISBN: 9780080526171
  • Genre: Science
  • Nombre de pages: 368
  • Langue: French/English
  • Vues: 1624
  • Telecharger: 1624
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Détails: The Genetical Theory of Natural Selection by R.A. Fisher (1930) dictated that sexual dimorphisms may depend upon a single medelian factor. This could be true for some species but his suggestion could not take off the ground as gender in Drosophila is determined by the number of X chromosomes. Technical advances in molecular biology have revived the initial thinking of Fisher and dictate that TDF or SRY genes in humans or Tdy in mice are sex determining genes. The fortuitous findings of XX males and XY female, which are generally termed sex reversal phenomenon, are quite bewildering traits that have caused much amazement concerning the pairing mechanism(s) of the pseudoautosomal regions of human X and Y chromosomes at meiosis. These findings have opened new avenues to explore further the genetic basis of sex determination at the single gene level. The aim of the fourth volume, titled Genetics of Sex Determination is to reflect on the latest advances and future investigative directions, encompassing 10 chapters. Commissioned several distinguished scientists, all pre-eminent authorities in each field to shed their thoughts concisely but epitomise their chapters with an extended bibliography. Obviously, during the past 60 years, the metoric advances are voluminous and to cover every account of genes, chromosomes, and sex in a single volume format would be a herculean task. Therefore, a few specific topics are chosen, which may be of great interest to scientists and clinicians. The seasoned scientists who love to inquire about the role of genes in sex determination should find the original work of these notable contributors very enlightening. This volume is intended for advanced students who want to keep abreast as well as for those who indulge in the search for genes of sex determination.


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